EDUCATION AND EMPLOYMENT
College of Chemistry and Molecular Sciences, Wuhan University, B.S., 2009-2013, supervisor Dr. Xiang Zhou
College of Chemistry and Molecular Sciences, Wuhan University, Ph.D., 2013-2018, supervisor Dr. Xiang Zhou
College of Chemistry and Molecular Sciences, Wuhan University, Postdoc, 2018-2022, supervisor Dr. Xiang Zhou and Dr. Yuqi Feng
College of Chemistry and Molecular Sciences, Wuhan University, Distinguished Associate Research Fellow, 2022-
RESEARCH FIELD
Research interests include the interaction between mesoporous materials and nucleic acids and their applications in biomedicine. The development of efficient nucleic acid isolation, enrichment, delivery and detection technologies aims to provide solutions to problems existing in the process of disease mechanism research, diagnosis and treatment.
PROJECTS
1. Host Youth Fund Project: Explore the enrichment of small RNA and RNA-protein complexes by metal-organic framework materials and their application in RNA sequencing, the National Natural Science Foundation of China
2. Host Postdoctoral Innovation Talent Support Program: Functional study of Cas13a protein in cells and its RNA tracing
3. Host General Program of China Postdoctoral Science Foundation: Functional study and application of Cas13a protein
AWARDS AND HONORS
1. Postdoctoral Innovation Talent Support Program, 2018
2. "China Telecom Scholarship Tianyi Award"/ "Advanced Individual Model for Practicing Socialist Core Values", 2018
3. First Prize of the 13th Challenge Cup National University Students Extracurricular Academic Science and Technology Works Competition, (1/4), 2013
4. Grand Prize of the 9th Hubei University Students Extracurricular Academic Science and Technology works Competition, 2013
PUBLICATIONS
1. Peng, S. #; Bie, B. #; Jia, H.; Tang, H.; Zhang, X.; Sun, Y.; Wei, Q.; Wu, F.; Yuan, Y.; Deng, H.*; Zhou, X.*, Efficient Separation of Nucleic Acids with Different Secondary Structures by Metal–Organic Frameworks. Journal of the American Chemical Society 2020, 142 (11), 5049-5059.
2. Peng, S. #; Liu, M. #; Bie, B.; Zhang, Y.; Tang, H.; Sun, Y.; Zhou, X.*, Multiplexed microRNA Detection Using Metal–Organic Framework for Signal Output. ACS Applied Bio Materials 2020, 3 (5), 2604-2609.
3. Peng, S.#; Bie, B.#; Sun, Y.; Liu, M.; Cong, H.; Zhou, W.; Xia, Y.; Tang, H.; Deng, H.*; Zhou, X.* Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells. Nature Communications, 2018, 9, 1293.
4. He, Z.; Peng, S.; Wei, Q.; Jia, S.; Guo, S.; Chen, K.; Zhou, X.*, Metabolic Labeling and Imaging of Cellular RNA via Bioorthogonal Cyclopropene−Tetrazine Ligation. CCS Chemistry 2020, 2, 89 –97
5. Chen, Y.#; Yang, S.#; Peng, S.; Li, W.; Wu, F.; Yao, Q.; Wang, F.; Weng, X.*; Zhou, X.*, N1-Methyladenosine detection with CRISPR-Cas13a/C2c2. Chemical Science, 2019, 10, 2975-2979.
